Profile of susceptibility in vitro of Trichosporon asahii and Trichosporon inkin strains against cyclic imides

Authors

  • Zélia Braz Vieira da Silva Pontes Universidade Federal da Paraíba; Centro de Ciências da Saúde; Departamento de Ciências Farmacêuticas; Laboratório de Micologia
  • Edeltrudes de Oliveira Lima Universidade Federal da Paraíba; Centro de Ciências da Saúde; Departamento de Ciências Farmacêuticas; Laboratório de Micologia
  • Valdir Cechinel Filho Universidade do Vale do Itajaí; Departamento de Química; Núcleo de Investigação Químico-Farmacêutica

DOI:

https://doi.org/10.1590/S1516-93322007000200014

Keywords:

Antifungals, Trichosporon asahii, Trichosporon inkin, Cyclic imides

Abstract

In vitro susceptibility testing of Trichosporon asahii (13 strains) and T. inkin (13 strains) against cyclic imides (succinimides, naphtalimides and maleimides) in concentrations of 200 to 6,25 µg/mL was performed according to the diffusion agar method. By the results obtained, the antifungal activity of the cyclic imides: 3,4-dichloro-N-phenyl-maleimide; 3,4-dichloro-N-phenyl-ethyl-maleimide and 3,4-dichloro-N-phenyl-propyl-maleimide (50 µg/mL) over T. asahii and T. inkin was important and it may be helpful in showing perspectives in a search for new antimicotic products.

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Published

2007-06-01

Issue

Vol. 43 No. 2 (2007)

Section

Original Papers

How to Cite

Profile of susceptibility in vitro of Trichosporon asahii and Trichosporon inkin strains against cyclic imides. (2007). Revista Brasileira De Ciências Farmacêuticas, 43(2), 273-279. https://doi.org/10.1590/S1516-93322007000200014