MOLECULAR CHARACTERIZATION OF AMERICAN CUTANEOUS LEISHMANIASIS IN THE TRI‑BORDER AREA OF ASSIS BRASIL, ACRE STATE, BRAZIL
AbstractIn this study, Leishmaniaspecies were identified by Polymerase Chain Reaction (PCR). The epidemiology of patients suspected of having American Cutaneous Leishmaniasis in the municipality of Assis Brasil, Acre State, located in the Brazil/Peru/Bolivia triborder was also investigated. By PCR, the DNA of Leishmaniawas detected in 100% of the cases (37 samples) and a PCR-Restriction Fragment Length Polymorphism (RFLP) of the hsp 70gene identified the species in 32 samples: Leishmania (Viannia) braziliensis (65.6%) , L. (V.) shawi (28.1%) , L. (V.) guyanensis (3.1%) and mixed infection L. (V.) guyanensisand L. (Leishmania) amazonensis(3.1%)This is the first report of L. (V.) shawiand L. (L.) amazonensisin Acre. The two predominant species were found in patients living in urban and rural areas. Most cases were found in males living in rural areas for at least three years and involved in rural work. This suggests, in most cases, a possible transmission of the disease from a rural/forest source, although some patients had not engaged in activities associated with permanence in forestall areas, which indicate a possible sandflies adaptation to the periurban setting.
Download data is not yet available.
How to Cite
TELES, C. B. G., MEDEIROS, J. F., SANTOS, A. P. de A. dos, FREITAS, L. A. R. de, KATSURAGAWA, T. H., CANTANHÊDE, L. M., FERREIRA, R. de G. M., & CAMARG, L. M. A. (2015). MOLECULAR CHARACTERIZATION OF AMERICAN CUTANEOUS LEISHMANIASIS IN THE TRI‑BORDER AREA OF ASSIS BRASIL, ACRE STATE, BRAZIL. Revista Do Instituto De Medicina Tropical De São Paulo, 57(4), 343-347. Retrieved from https://www.revistas.usp.br/rimtsp/article/view/105547