Comparative study of adenoviruses with monoclonal antibodies
Keywords:Adenovirus, Species Specific, Monoclonal antibodies, Adenovirus 4, Antigenic Relationship
AbstractThe obtainment of monoclonal antibodies for adenovirus species 4(Ad4) is described.The specificities of selected monoclonal antibodies were determined by means of viral neutralization test in cell culture, immunofluorescence and Enzyme-Linked Immunosorbent Assay (ELISA), in the presence of the following species of human adenovirus: 1, 2, 5 (subgenus C), 4 (subgenus E), 7 and 16 (subgenus B) and 9 (subgenus D). Two monoclonal antibodies species specific to adenovirus 4 (1CIII and 3DIII) and one monoclonal antibody that cross reacted with adenovirus species 4 and 7 (2HIII) were obtained.
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Paiva, T. M. de, Takimoto, S., Ishida, M. A., Souza, M. C. O. de, Ishimaru, T., Neumann, J., & Kalil, J. (1992). Comparative study of adenoviruses with monoclonal antibodies . Revista Do Instituto De Medicina Tropical De São Paulo, 34(1), 19-26. Retrieved from https://www.revistas.usp.br/rimtsp/article/view/28886