Secondary dengue infection in schoolchildren in a dengue endemic area in the State of Rio de Janeiro, Brazil
Keywords:
Dengue, secondary infection, Epidemiology, BrazilAbstract
A seroepidemiologic survey was carried out in schoolchildren from public schools of the Niterói municipality, state of Rio de Janeiro, Brazil, after a period of sequential epidemics by dengue virus type 1 and 2 (DEN-1 and DEN-2). 450 blood samples were obtained by fingertip puncture and collected on filter paper discs. The hemagglutination inhibition (HAI) test was carried out using DEN-1 and DEN-2 antigens. HAI titres were demonstrated in 66% (297/450) of the sera and the geometric means of the titres were 1/182 and 1/71 for DEN-1 and DEN-2, respectively. Secondary infections were observed in 61% (181/297) of positive cases. Among these, 75% (135/181) were under fifteen years old. No dengue haemorrhagic fever (DHF) was reported in these children. Asymptomatic or oligosymptomatic infections were detected in 56% of the studied population. The absolute and relative frequencies of positive tests by age group and sex did not evidence statistically significant difference. The number of individuals infected probably produced a immunologic barrier responsible for the non occurrence of dengue epidemic in the latter years.Downloads
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Published
1995-12-01
Issue
Section
Soroepidemiology
How to Cite
Cunha, R. V. da, Dias, M., Nogueira, R. M. R., Chagas, N., Miagostovich, M. P., & Schtzmayr, H. G. (1995). Secondary dengue infection in schoolchildren in a dengue endemic area in the State of Rio de Janeiro, Brazil . Revista Do Instituto De Medicina Tropical De São Paulo, 37(6), 517-521. https://www.revistas.usp.br/rimtsp/article/view/29321