Subcutaneoous phaeohyphomycosis by Exophiala jeanselmei in a cardiac transplant recipient

Authors

  • Maria do Rosário R. Silva UFG; IPTSP; Departamento de Microbiologia, Imunologia, Parasitologia e Patologia
  • Orionalda de F.L. Fernandes UFG; IPTSP; Departamento de Microbiologia, Imunologia, Parasitologia e Patologia
  • Carolina R. Costa UFG; IPTSP; Departamento de Microbiologia, Imunologia, Parasitologia e Patologia
  • Aiçar Chaul UFG; IPTSP; Departamento de Microbiologia, Imunologia, Parasitologia e Patologia
  • Luciano F. Morgado UFG; IPTSP; Departamento de Medicina Tropical
  • Luis Fernando Fleury-Júnior UFG; IPTSP; Departamento de Medicina Tropical
  • Maurício B. Costa UFG; Faculdade de Medicina; Departamento de Patologia e Imagenologia

Keywords:

Exophiala jeanselmei, Phaeohyphomycosis, Subcutaneous infections

Abstract

We report a case of phaeohyphomycosis caused by Exophiala jeanselmei in a cardiac transplant recipient maintained on immunosuppressive therapy with mycophenolate mofetil tacrolimus and prednisone. The lesion began after trauma on the right leg that evolved to multiple lesions with nodules and ulcers. Diagnosis was performed by histological examination and culture of pus from skin lesions. Treatment consisted of itraconazole (200 mg/day) for three months with no improvement and subsequently with amphotericin B (0.5 mg/Kg per day to a total of 3.8 g intravenously). After four months of treatment, the lesions showed marked improvement with reduction in the swelling and healing of sinuses and residual scaring.

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Published

2005-02-01

Issue

Section

Case Report

How to Cite

Silva, M. do R. R., Fernandes, O. de F., Costa, C. R., Chaul, A., Morgado, L. F., Fleury-Júnior, L. F., & Costa, M. B. (2005). Subcutaneoous phaeohyphomycosis by Exophiala jeanselmei in a cardiac transplant recipient . Revista Do Instituto De Medicina Tropical De São Paulo, 47(1), 55-57. https://www.revistas.usp.br/rimtsp/article/view/30884