Molecular identification of Candida dubliniensis isolated from oral lesions of HIV-positive and HIV-negative patients in São Paulo, Brazil

Authors

  • Jorge Kleber Chavasco USP; ICB
  • Claudete Rodrigues Paula Universidade de São Paulo; Instituto de Ciências Biomédicas; Departamento de Microbiologia
  • Mario Hiroyuki Hirata Universidade de São Paulo; Departamento de Análises Clínicas
  • Natanael Atilas Aleva UNINCOR
  • Carlos Eduardo de Melo Universidade de São Paulo; Departamento de Análises Clínicas
  • Walderez Gambale Universidade de São Paulo; Instituto de Ciências Biomédicas; Departamento de Microbiologia
  • Luciana da Silva Ruiz Universidade de São Paulo; Instituto de Ciências Biomédicas; Departamento de Microbiologia
  • Marília Caixeta Franco Universidade Federal de Alfenas

Keywords:

HIV-positive, HIV-negative, Candida dubliniensis, PCR

Abstract

Candida dubliniensis is a new, recently described species of yeast. This emerging oral pathogen shares many phenotypic and biochemical characteristics with C. albicans, making it hard to differentiate between them, although they are genotypically distinct. In this study, PCR (Polymerase Chain Reaction) was used to investigate the presence of C. dubliniensis in samples in a culture collection, which had been isolated from HIV-positive and HIV-negative patients with oral erythematous candidiasis. From a total of 37 samples previously identified as C. albicans by the classical method, two samples of C. dubliniensis (5.4%) were found through the use of PCR. This study underscores the presence of C. dubliniensis, whose geographical and epidemiological distribution should be more fully investigated.

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Published

2006-02-01

Issue

Vol. 48 No. 1 (2006)

Section

Mycology

How to Cite

Chavasco, J. K., Paula, C. R., Hirata, M. H., Aleva, N. A., Melo, C. E. de, Gambale, W., Ruiz, L. da S., & Franco, M. C. (2006). Molecular identification of Candida dubliniensis isolated from oral lesions of HIV-positive and HIV-negative patients in São Paulo, Brazil . Revista Do Instituto De Medicina Tropical De São Paulo, 48(1), 21-26. https://www.revistas.usp.br/rimtsp/article/view/30963