Treatment of severe chromoblastomycosis with itraconazole and 5-flucytosine association

Authors

  • Vicente Sperb Antonello Hospital Nossa Senhora da Conceição; Department of Infectious Diseases
  • Marcelo Campos Appel da Silva Hospital Nossa Senhora da Conceição; Department of Internal Medicine
  • Eduardo Cambruzzi Hospital Nossa Senhora da Conceição; Department of Pathology
  • Dimas Alexandre Kliemann Hospital Nossa Senhora da Conceição; Department of Infectious Diseases
  • Breno Riegel Santos Hospital Nossa Senhora da Conceição; Department of Infectious Diseases
  • Flávio Queiroz-Telles Universidade Federal do Paraná; Hospital de Clinicas; Department of Community Health and Infectious Diseases

Keywords:

Chromoblastomycosis, Itraconazole, 5-Flucytosine, Subcutaneous mycoses

Abstract

Chromoblastomycosis is a chronic human melanized fungi infection of the subcutaneous tissue caused by traumatic inoculation of a specific group of dematiaceous fungi through the skin, often found in barefooted agricultural workers, in tropical and subtropical climate countries. We report the case of a male patient presenting a slow-growing pruriginous lesion on the limbs for 20 years, mistreated over that time, which was diagnosed and successfully treated as chromoblastomycosis. Besides the prevalence of this disease, treatment is still a clinical challenge.

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Published

2010-12-01

Issue

Vol. 52 No. 6 (2010)

Section

Case Reports

How to Cite

Antonello, V. S., Silva, M. C. A. da, Cambruzzi, E., Kliemann, D. A., Santos, B. R., & Queiroz-Telles, F. (2010). Treatment of severe chromoblastomycosis with itraconazole and 5-flucytosine association . Revista Do Instituto De Medicina Tropical De São Paulo, 52(6), 329-331. https://www.revistas.usp.br/rimtsp/article/view/31363