Effect of thalidomide on serum levels of immunoglobulins IgM and IgA, rheumatoid factor and isohemaglutinins anti-A and anti-B in patients with lepromatous leprosy: a double-blind study

Authors

  • Walter Oleschko Arruda Universidade Federal do Paraná; Hospital de Clínicas; Laboratório de Imunopatologia
  • Elisa Hacbarth Universidade Federal do Paraná; Hospital de Clínicas; Laboratório de Imunopatologia
  • Elvira Döi Universidade Federal do Paraná; Hospital de Clínicas; Laboratório de Imunopatologia
  • Jesus R. Santa-Maria Fundação Caetano Munhoz da Rocha; Hospital Dermatológico-Sanitário São Roque
  • Jânio Barbosa Universidade Federal do Paraná; Hospital de Clínicas; Laboratório de Imunopatologia
  • André A. Kajdacsy-Balla Universidade Federal do Paraná; Hospital de Clínicas; Laboratório de Imunopatologia

Abstract

A double-blind study was performed in a group of patients with lepromatous leprosy to evaluate the response of IgM and IgA serum levels and of serum titles of rheumatoid factor and isohemaglutinins anti-A and anti-B to administration of thalidomide 100 mg each day, for 18 days. No significant effect was detected at the end of the study.

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Published

1986-02-01

Issue

Vol. 28 No. 1 (1986)

Section

Original Articles

How to Cite

Arruda, W. O., Hacbarth, E., Döi, E., Santa-Maria, J. R., Barbosa, J., & Kajdacsy-Balla, A. A. (1986). Effect of thalidomide on serum levels of immunoglobulins IgM and IgA, rheumatoid factor and isohemaglutinins anti-A and anti-B in patients with lepromatous leprosy: a double-blind study . Revista Do Instituto De Medicina Tropical De São Paulo, 28(1), 12-14. https://www.revistas.usp.br/rimtsp/article/view/87456