Factors associated with acquisition of carbapenem-resistant Enterobacteriaceae

Authors

  • Lilian Silva Lavagnoli Secretaria de Saúde; Laboratório de Microbiologia Médica
  • Bil Randerson Bassetti Hospital Estadual Central
  • Thais Dias Lemos Kaiser Secretaria de Saúde; Laboratório de Microbiologia Médica
  • Kátia Maria Kutz Hospital Santa Casa de Misericóridia de Vitória
  • Crispim Cerutti Junior Universidade Federal do Espírito Santo

DOI:

https://doi.org/10.1590/1518-8345.1751.2935

Keywords:

Enterobacteriaceae, Drug Resistance, Microbial, Risk Factors, Epidemiology, Dissemination of Resistance, Hospital Environment

Abstract

Objective: to identify possible risk factors for acquisition of Enterobacterial strains with a marker for resistance to carbapenems. Methods: exploratory case-control study performed in hospital settings. The study sample consisted of patients with biological specimens that tested positive for carbapenem-resistant Enterobacteriaceae (cases), with the disk diffusion test and Etest, and controls with biological samples testing negative for carbapenem-resistant Enterobacteriaceae. In all, 65 patients were included: 13 (20%) cases and 52 (80%) controls. Results: the microorganisms isolated were Serratia marcescens (6), Klebsiella pneumoniae (4), and Enterobacter cloacae (3). Univariate analysis revealed that length of hospitalization prior to sample collection (p=0.002) and having a surgical procedure (p=0.006) were statistically significant. In the multivariable logistic regression model, both were still significant, with odds ratios of 0.93 (p = 0.009; 95% CI: 0.89 to 0.98) for length of hospitalization prior to sample collection, and 9.28 (p = 0.05; 95% CI: 1.01 to 85.14) for having a surgical procedure. Conclusion: shorter hospitalization times and increased surveillance of patients undergoing surgery could play a decisive role in reducing the spread of carbapenem-resistant microorganisms in hospital settings.

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Published

2017-01-01

Issue

Vol. 25 (2017)

Section

Original Articles

License

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Including names of authors whose contribution does not fit into the above criteria cannot be justified. Those names can be included in the Acknowledgements section.
 Authors are fully responsible for the concepts disseminated in their manuscripts, which do not necessarily reflect the editors’ and editorial board’s opinion.

 

How to Cite

Factors associated with acquisition of carbapenem-resistant Enterobacteriaceae. (2017). Revista Latino-Americana De Enfermagem, 25, e2935-. https://doi.org/10.1590/1518-8345.1751.2935