Anthelmintic efficacy of three doses of an association of pyrantel pamoate plus, oxantel pamoate and praziquantel in naturally infected cats

Authors

  • Solange Maria Gennari Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Medicina Preventiva e Saúde Animal, São Paulo, SP
  • Nobuko Kasai Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Medicina Preventiva e Saúde Animal, São Paulo, SP
  • Sandra Mayumi Nishi
  • Hilda Fatima de Jesus Pena

DOI:

https://doi.org/10.11606/bjvras.v34i5.50337

Keywords:

Cats, Pyrantel pamoate, Oxantel, Praziquantel, Helmintos.

Abstract

The purpose of this study was to evaluate the anthelmintic activity of three different doses of an association of pyrantel pamoate, oxantel pamoate and praziquantel in a single oral dose, in naturally infected cats. Animals were obtained from the Centro de Controle de Zoonoses, from Diadema, São Paulo, and divided in four groups each of eight cats, based on pretreatment faecal examination. Group 1: untreated control cats; Group 2: 5 mg of pyrantel pamoate, 5 mg of oxantel pamoate and 2.5 mg of praziquantel/kg body weight (BW); Group 3: 10 mg of pyrantel pamoate, 10 mg of oxantel pamoate and 5 mg of praziquantel/kg BW and Group 4:20 mg of pyrantel pamoate, 20 mg of oxantel pamoate and 10 mg of praziquantel/kg BW. The percentage of reduction in egg counts and percentage of efficacy were calculated. Mean egg counts from all treated cats decreased significantly from the second day after treatment on. The number of immature Toxocara cati and Ancylostoma spp. worms also decreased, however it was not significant. The number of adult worms decreased significantly in the treated groups. The percentage of efficacy for Toxocara cati was 93.0%, 97.6% and 100.0% and for Ancylostoma spp. was 96.5%, 99.0% and 100.0%, for groups 2,3 and 4, respectively. The compound was effective against Dipylidium caninum and ineffective
against Physaloptera spp. and Strongyloides stercoraiis in a single dose.

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Published

1997-10-01

How to Cite

Gennari, S. M., Kasai, N., Nishi, S. M., & Pena, H. F. de J. (1997). Anthelmintic efficacy of three doses of an association of pyrantel pamoate plus, oxantel pamoate and praziquantel in naturally infected cats. Brazilian Journal of Veterinary Research and Animal Science, 34(5), 284-287. https://doi.org/10.11606/bjvras.v34i5.50337

Issue

Section

ANIMAL PATHOLOGY

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