Anátomo histopathologic evaluation of the effect of medroxiprogesterone acetate and megestrol acetate on the uterus of adult bitches
Keywords:Hedroxi progesterone acetate, Megestrol acetate, Endometritis of bitches
In this trial, 18 adult clinically sound bitches, without clinical symptoms of estrus were utilized, being randomly assigned in 6 groups with 3 animals each. After uterine biopsy for control, medroxiprogesterone acetate was injected into females of the group I, II and III, and megestrol acetate into females of the group IV, V and VI. It was observed that both drugs were capable in inducing endometritis, but this effect was more discrete in the animals of group IV, V and VI. The occurrence of poliuria, polidipsia, abdominal distention, purulent or bloody vaginal secretion, leucocitosis or anemia was not recorded.
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