Biologic and immunologic characterization of rabies virus isolates of domestic animals from rabies endemic areas of Brazil

Authors

  • Paulo Roberto de Oliveira Universidade Federal de Uberlândia, MG.
  • Fumio Honma Ito Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP.
  • José de Angelis Côrtes Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP.
  • Silvio Arruda Vasconcellos Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP.
  • Maria da Conceição Aparecida Macedo Souza Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP.

DOI:

https://doi.org/10.11606/issn.1678-4456.bjvras.1994.52093

Keywords:

Zoonoses, Rabies, Rabies virus, Antigens (immunofluorescence)

Abstract

Biologic and immunologic profiles of rabies virus isolates obtained from domestic animals of endemic areas were compared to the CVS rabies virus by means of mice inoculation, serum-neutralization test and by the fluorescent antibody technique (FA). The mean incubation period was 10.2 days, with a range of 4 and 23 days; the disease period was found with a mean period of 3.3 days with a range of 1 and 5 days; the overall value of pathogenicity was 96.5% (332/344) and clinical manifestations all resembled rabies. All rabies virus isolates have reacted specifically to FA test and they all revealed immunologic identity to the standard strain of the CVS virus through the serum-neutralization technique.

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Published

1995-06-02

How to Cite

Oliveira, P. R. de, Ito, F. H., Côrtes, J. de A., Vasconcellos, S. A., & Souza, M. da C. A. M. (1995). Biologic and immunologic characterization of rabies virus isolates of domestic animals from rabies endemic areas of Brazil. Brazilian Journal of Veterinary Research and Animal Science, 32(2), 89-95. https://doi.org/10.11606/issn.1678-4456.bjvras.1994.52093

Issue

Section

PREVENTIVE VETERINARY MEDICINE