Case report and immunohistochemical study of a malignant peripheral nerve sheath tumor in a dog
Keywords:Neoplasm, Pelvic member, Canine, Markers
Malignant peripheral nerve sheath tumor is rare and rarely reported in dogs. The term neurofibroma/sarcoma is classically used when the tumor is composed of Schawann and perineural cells. This work describes the clinical, histopathological, and immunohistochemical case of a subcutaneous malignant peripheral nerve sheath tumor, most likely a malignant neurofibroma located in the pelvic member of a Rottweiler dog. Histopathological features and immunohistochemical analysis corroborated the diagnosis, showing positivity for S-100 protein, vimentin, and CD57, and was useful to distinguish this type of neoplasm from other malignancies of similar morphologies.
How to Cite
The journal content is authorized under the Creative Commons BY-NC-SA license (summary of the license: https://