Evaluation of the effects of epidural amitraz in cows
Keywords:Alfa-2 agonist, Amitraz, Analgesia, Cattle, Epidural
AbstractThe amitraz is widely used in veterinary medicine as an acaricide in small and large animals. Several reports showed that the systemic effects caused by epidural administration of this substance are the result of its interaction with a-2 adrenoceptors. In the present study, the effects of epidurally amitraz (0,1 or 0,4 mg.kg-1) or 10% DMSO (5,0 mL) on the heart rate (HR), systolic arterial pressure (SAP), respiratory rate (RR), ruminal motility (RM), rectal temperature (RT), head height (HH), and latency to heat-evoked reflexes (LSPR - skin of perineal region; LHWR - hoof withdrawal reflex) were evaluated. The HR and RM decreased in amitraz groups. There were no statistical differences in RR, SAP and HH among groups. LSPR and LHWR were prolonged in amitraz 0,4 group (T25-T120). We concluded that epidural amitraz does not produce severe systemic effects, and that the higher dose induces prolongation of the latency to heat-evoked reflexes, in cows.
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