Effects of endosulfan sublethal concentrations on carp (Cyprinus carpio, Linnaeus, 1758): Morphometric, hystologic, ultrastructural analyses and cholinesterase activity evaluation

Authors

  • Lígia Maria Salvo Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia, São Paulo, SP
  • Idércio Luiz Sinhorini Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia, São Paulo, SP
  • Benjamim Eurico Malucelli Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Patologia, São Paulo, SP
  • Cláudio Klemz Universidade Federal do Paraná, Departamento de Farmacologia -Toxicologia Ambiental Aquática, Curitiba, PR
  • Delia Carolina Olmedo Sanchez Universidade Federal do Paraná, Departamento de Farmacologia -Toxicologia Ambiental Aquática, Curitiba, PR
  • Lílian Nicaretta Universidade Federal do Paraná, Departamento de Farmacologia -Toxicologia Ambiental Aquática, Curitiba, PR
  • Maria Ivette Carboni Malucelli Instituto Butantan, São Paulo, SP
  • Metry Bacila Pontifícia Universidade Católica do Paraná, Centro de Ciências Biológicas e da Saúde, Curitiba, PR
  • Helena Cristina Silva de Assis Universidade Federal do Paraná, Departamento de Farmacologia -Toxicologia Ambiental Aquática, Curitiba, PR

DOI:

https://doi.org/10.11606/issn.1678-4456.bjvras.2008.26704

Keywords:

Endosulfan, Fish, Cyprinus carpio, Cholinesterase, Ultrastructural analyse

Abstract

Endosulfan, an organochlorine pesticide, has been banned by most developed countries, although it is still produced, sold and used in developing countries. Used for control in crops, as well as for insect control in public health programs in some countries, its effects on the environment and its toxicity are still in discussion. For some researchers, its bioaccumulation in terrestrial organisms is considered irrelevant but for aquatic life it should be considered carefully. The present research work was to carry out an study on the effects of sublethal concentrations of endosulfan on the fresh water fish carp (Cyprinus carpio, Linnaeus, 1758). The fishes were exposed during 15 days to 0.001 mg/L of endosulfan using dimethylsulfoxide 0.1% (DMSO) as solvent. The acetylcholinesterase activity on the brain and axial muscle, as well as liver morphometric, histopathologic and ultrastructural analysis were studied. The hepatic somatic index and the livers weight showed smaller values when compared with the control groups, besides being also observed histopathological and ultrastructural alterations. It has not been observed significant alterations in the cholinesterase activity of both brain and striated muscle. These results suggest that the organochloride endosulfan caused toxic effects in the hepatic metabolism of the fish exposed to it in sub lethal doses.

Downloads

Download data is not yet available.

Downloads

Published

2008-04-01

Issue

Section

UNDEFINIED

How to Cite

1.
Salvo LM, Sinhorini IL, Malucelli BE, Klemz C, Sanchez DCO, Nicaretta L, et al. Effects of endosulfan sublethal concentrations on carp (Cyprinus carpio, Linnaeus, 1758): Morphometric, hystologic, ultrastructural analyses and cholinesterase activity evaluation. Braz. J. Vet. Res. Anim. Sci. [Internet]. 2008 Apr. 1 [cited 2024 May 18];45(2):87-94. Available from: https://www.revistas.usp.br/bjvras/article/view/26704