Participation of a non-peptide adrenergic agent on positive inotropic effect of the polar fraction of Bryopsis pennata

Authors

  • Andrea Lucia Natali Oliani Universidade de São Paulo, Instituto de Biociências, São Paulo, SP
  • Jeanete Lopes Naves Universidade de São Paulo, Instituto de Biociências, São Paulo, SP
  • José Carlos de Freitas Universidade de São Paulo, Instituto de Biociências, São Paulo, SP
  • Claudio Alvarenga Oliveira Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, São Paulo, SP

DOI:

https://doi.org/10.11606/issn.1678-4456.bjvras.2010.26837

Keywords:

Bryopsis pennata, Inotropic positive, Propranolol

Abstract

Marine algae are a rich source of bioactive compounds and some of them have shown to be useful for the development of new pharmacological tools and medicines. Bryopsis pennata, (Clorofícea, Caulerpales, sin. Bryopsidales) is a marine algae that can be found in the Southeastern Brazilian coast and elsewhere. The species produces a toxic chemical defense to the herbivorous organisms and possesses a potential to become invasive and dominant in favorable environmental conditions.The present study is about the investigation of the cardiotonic effect of the polar extract of B. pennata. The cultive in laboratory without any contaminants was made to compare studies performed with the collected algae extracts and the ones cultivated effect. The cardiotonic effect in the anurou's ventricular strips was strongly unequivocal when it was tested with the polar extracts from the collected and cultivated algae. The propranolol antagonized polar effects of these algae and the endopeptidase enzyme did not change the effects of polar extracts of Bryopsis pennata. Biochemical tests showed that the polar fraction presenting the inotropic cardiac activity weighs less than 10.000 Daltons and has an acid character.

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Published

2010-04-01

Issue

Section

UNDEFINIED

How to Cite

1.
Oliani ALN, Naves JL, Freitas JC de, Oliveira CA. Participation of a non-peptide adrenergic agent on positive inotropic effect of the polar fraction of Bryopsis pennata. Braz. J. Vet. Res. Anim. Sci. [Internet]. 2010 Apr. 1 [cited 2024 May 27];47(2):132-6. Available from: https://www.revistas.usp.br/bjvras/article/view/26837