Histochemical comparative study of primary and metastatic tumors in nude rats xenotransplanted with KB cells
Keywords:Extracellular matrix, KB cells, Histochemical, Nude rats
AbstractA comparative study of metastic and primitive tumors extra-celular matrix in nude rats, xenotransplanted with KB cells, using histochemical methods, was carried out. In both primitive and metastatic tumors it was possible to observe a qualitative and a quantitative variation of matricial components; coexistence of different kinds of fibers; small representation of elastic fibers; presence of acid and sulfated glycosaminoglycans and neutral polysacharyds, and also absence of basal membrane. It is suggested a small interaction between collagenic components and proteoglycan of primary tumors and the proteoglycan, whereas in métastasés this interaction is increased.
How to Cite
The journal content is authorized under the Creative Commons BY-NC-SA license (summary of the license: https://