Study of the frequency on the dog erythrocyte antigen 1, 1.1 and 7 and incompatible transfusion risk in different dog breeds and mongrel dogs of the metropolitan region of São Paulo-SP, Brazil

Authors

  • Samantha Leite de Souza Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia
  • Angelo João Stopiglia Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia
  • Simone Gonçalves Rodrigues Gomes Universidade Santo Amaro - UNISA; Hemovet, Laboratório e Centro de Hemoterapia Veterinária
  • Silvia Kana Ulata Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia
  • Ludmila Rodrigues Moroz Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia
  • Denise Tabacchi Fantoni Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia

DOI:

https://doi.org/10.11606/issn.1678-4456.v51i4p316-323

Keywords:

Canine blood typing, Dogs, DEA, Transfusion risk, Transfusion medicine veterinary

Abstract

This study aims to investigate the frequency of blood groups identified as Dog Erythrocyte Antigens (DEA) 1, 1.1 and 7 dogs in the metropolitan region of São Paulo-SP, Brazil, and calculate the risk of administering incompatible blood in both first and second transfusion. For both, 300 unrelated dogs were equally divided into six groups according to the breeds: German Shepherd (GS), Rottweiler (R) Poodle (P), Cocker Spaniel (CS); defined several races (DSR), mongrel dogs (M). We evaluated the relationship between the frequency of AEC and racial groups. The overall frequency of DEA 1 in population was 71% (DEA 1.1 – 53.35%) and there were variations according to the breeds: GS- 32% (DEA 1.1 – 20%), R –98% (1.1 – 80%) P – 76% (1.1 – 54%), CS-84% (1.1 – 50%), DSR- 62% (1.1 – 56%) and M –- 74% (1.1 – 60%). The overall frequency of BCE 7 was 39.33%, and there were no significant differences between the breeds. The risk of a dog negative DEA receiving 1 positive blood was 0.6 to 66.6% in the first transfusion and 0.21 to 65.3% from the same animal dog receiving incompatible blood transfusion in a second. The risk of the DEA 7 was 23.86% in the first transfusion and 9.4% in a second transfusion. This study concluded that there was variation in the frequency of DEA 1 and 1.1, but not on the DEA 7 between races. This variation in the percentage of positive animals to DEA 1 was reflected in the large variation in the risk of use of incompatible blood. Therefore, knowing the frequency of the DEA in the population has a direct impact on handling dogs between donors and recipients, but the joint use of testing blood typing and cross-reactivity reduces the possibility of incompatible blood transfusion.

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Author Biographies

  • Simone Gonçalves Rodrigues Gomes, Universidade Santo Amaro - UNISA; Hemovet, Laboratório e Centro de Hemoterapia Veterinária
    Prof.a Dr.a pelo Departamento de Cirurgia - VCI, Faculdade de Medicina Veterinária e Zootecnia - FMVZ - USP
  • Ludmila Rodrigues Moroz, Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia
    Médica Veterinária, doutoranda do Departamento de Cirurgia Animal da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo
  • Denise Tabacchi Fantoni, Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Cirurgia
    Médica Veterinária, Professora Titular do Departamento de Cirurgia - VCI, Faculdade de Medicina Veterinária e Zootecnia - FMVZ - USP

Published

2015-02-06

Issue

Section

ARTICLES

How to Cite

1.
de Souza SL, Stopiglia AJ, Gomes SGR, Ulata SK, Moroz LR, Fantoni DT. Study of the frequency on the dog erythrocyte antigen 1, 1.1 and 7 and incompatible transfusion risk in different dog breeds and mongrel dogs of the metropolitan region of São Paulo-SP, Brazil. Braz. J. Vet. Res. Anim. Sci. [Internet]. 2015 Feb. 6 [cited 2024 Jun. 16];51(4):316-23. Available from: https://www.revistas.usp.br/bjvras/article/view/58317