Hematological, respiratory and cardiovascular response of equine submitted to three anesthetic protocols


  • João Roberto Braga de Mello Universidade Federal do Rio Grande do Sul, Instituto de Ciências Básicas, Departamento de Farmacologia
  • Jarbas Francisco de Castro Junior Jockey Club do Rio Grande do Sul, Hospital Veterinário 'Dr. Joaquim Araújo'
  • Antônio da Pádua Ferreira da Silva Filho Universidade Federal do Rio Grande do Sul, Faculdade de Veterinária, Departamento de Medicina Animal




Anesthesia, Equine, Guaifenesin, Ketamine


This research studied the hematological, respiratory and cardiocirculatory effects in thoroughbred equine subjects after the administration of 3 different induction protocols for general anesthesia. The animals were distributed in 3 groups. The animals from group 1 (G1) received acepromazine (0.1 mg/kg), guaiphenesin (113 mg/kg) and thiopental (2 g). The animals from group 2 (G2) received levomepromazin (0.2 mg/kg), midazolam (0.1 mg/kg) and ketamine (2.0 mg/kg). The animals from group 3 (G3) received detomidine (20 µg/kg) and tiletamine-zolazepam (1.1 mg/kg). The evaluation included clinical examination, venous blood samples for hematological analysis, arterial blood samples for gasometric analysis and eletrocardiographic records. Clinical parameters were observed, samples were taken and the ECG was recorded before any drug administration and 15 minutes after the last medication. The 3 protocols showed to be adequate when used before general anesthesia. Respiratory parameters showed no differences among the 3 groups. The cardiocirculatory events were transient and without clinical significance. The differences among the groups were related to the preparation of solutions (G1), frequency in drug supplementation (G2) and handling the animals (G3).


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How to Cite

Mello JRB de, Castro Junior JF de, Silva Filho A da PF da. Hematological, respiratory and cardiovascular response of equine submitted to three anesthetic protocols. Braz. J. Vet. Res. Anim. Sci. [Internet]. 2000 Dec. 1 [cited 2024 Apr. 17];37(6):491-6. Available from: https://www.revistas.usp.br/bjvras/article/view/5868