Microbiological and therapeutic aspects of 180 infectious endocarditis patients occured in Ribeirão Preto between 1992 and 1997

Abstract

In this study, we analyzed bacteria isolates obtained from 180 infectious endocarditis cases occurred in Ribeirão Preto, SP, Brazil, between 1992 to 1997, including the antimicrobial drug sensitivity of these agents. Blood cultures were performed in 93,8% of the cases, and in 60,7% of them a microorganism has been isolated. The most commonly isolated bacteria were Staphylococcus aureus, 31,0 % (52/168), Streptococcus viridans, 15,9 % (27/168), Group D Streptococcus, 6,6 % (11/168), Gram negatives, 5,3 % (9/168), and Staphylococcus epidermidis, 4,2 % (7/168). All the Staphylococcus aureus, isolates were vancomycin and teicoplanyn sensitive, 86,5%, were aminoglycoside-sensitives, 85% were also first generation cephalosporinssensitives and 79% oxacillin-sensitives. Streptococcus viridans isolates were all chloramphenicolsensitives, vancomycin-sensitives and only 2 isolates were resistants to ampicillin and G penicillin. The Group D Streptococcus were all G penicillin, ampicillin, chloramphenicol and vancomycinsensitives.