Immunogenicity evaluation of proteins from a Mycobacterium bovis isolated from cattle in the State of Goiás, Brasil

Authors

  • Cinthya Marques Fortes Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO
  • Bruno Souza Marques Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO
  • Viviane Cambuí Mesquita Rocha Universidade de São Paulo, Faculdade de Medicina Veterinária e Zootecnia, Departamento de Medicina Veterinária Preventiva e Saúde Animal, São Paulo, SP
  • Ana Paula Junqueira-Kipnis Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO

DOI:

https://doi.org/10.11606/issn.2318-3659.v49i5p354-359

Keywords:

Bovine tuberculosis, Diagnostic, Proteins

Abstract

Bovine tuberculosis, persists in several countries as a threat to health of the herds despite the efforts given to the control and eradication of the disease. In order to detect immunogenic proteins with a potential to be used in a bovine tuberculosis diagnosis test, serum samples obtained from reactors and no reactors to intradermal tuberculin test, were evaluated for reactivity to Mycobacterium bovis antigens from a bacilli originated in Goiás – Brazil. The proteins immunogenicity from M. bovis was obtained by Western blot according to the molecular weight profile. The majority of the PPD positive bovine (67.92%) recognized a protein with 26kDa, suggesting the use of this protein in a serological test for bovine tuberculosis.

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Published

2012-10-26

How to Cite

Fortes, C. M., Marques, B. S., Rocha, V. C. M., & Junqueira-Kipnis, A. P. (2012). Immunogenicity evaluation of proteins from a Mycobacterium bovis isolated from cattle in the State of Goiás, Brasil. Brazilian Journal of Veterinary Research and Animal Science, 49(5), 354-359. https://doi.org/10.11606/issn.2318-3659.v49i5p354-359

Issue

Vol. 49 No. 5 (2012)

Section

UNDEFINIED

License

The journal content is authorized under the Creative Commons  BY-NC-SA  license (summary of the license: https://creativecommons.org/licenses/by-nc-sa/4.0 | full text of the license: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode)