Ganglionopathy as the initial manifestation of neoplastic lung disease: a case report

Authors

  • Caio Ribeiro Azevedo Gomes Faculdade de Medicina da Universidade de São Paulo
  • Bruno Nogueira Silva Faculdade de Medicina da Universidade de São Paulo
  • Gustavo Carneiro Ferrão Faculdade de Medicina da Universidade de São Paulo
  • Andressa Silvia Faé Nunes Faculdade de Medicina da Universidade de São Paulo
  • Arquimedes de Moura Ramos Faculdade de Medicina da Universidade de São Paulo
  • Tae Mo Chung Faculdade de Medicina da Universidade de São Paulo
  • Lucas Martins de Exel Nunes Faculdade de Medicina da Universidade de São Paulo

DOI:

https://doi.org/10.5935/0104-7795.20150040

Keywords:

Polyneuropathies, Lung Neoplasms, Case Reports

Abstract

Ganglionopathy is a rare condition defined by an injury to the sensory neurons in the dorsal root ganglion. This disease belongs to a group of peripheral polyneuropathies with an exclusively sensory and axonal pattern and its diagnoses can be made by an electromyoneurographic study. The association between ganglionopathy and other underlying pathologies, such as some types of cancer, autoimmune diseases, and celiac disease is often mentioned in published studies. The purpose of this report was to describe the case of a patient suffering from ganglionopathy including a detailed discussion of the electromyoneurographic study that led the attending physician to a diagnosis of neoplastic lung disease. The conclusion therefore was that it is important for the neurophysiology specialist to keep in mind the possible causes of ganglionopathy and, through this diagnosis, to help the attending physician in making an early and full workup of the patient.

Downloads

Download data is not yet available.

References

Félix EDV, Oliveira ASB. Diretrizes para abordagem diagnóstica das neuropatias em serviço de referência em doenças neuromusculares. Rev Neurocienc. 2010;18(1):74-80

Donofrio PD, Albers JW. AAEM minimonograph #34: polyneuropathy: classification by nerve conduction studies and electromyography. Muscle Nerve. 1990;13(10):889-903. DOI: http://dx.doi.org/10.1002/mus.8801310023

Marquez-Infante C, Murphy SM, Mathew L, Alsanousi A, Lunn MP, Brandner S, et al. Asymmetric sensory ganglionopathy: a case series. Muscle Nerve. 2013;48(1):145-50. DOI: http://dx.doi.org/10.1002/mus.237724

Kuntzer T, Antoine JC, Steck AJ. Clinical features and pathophysiological basis of sensory neuronopathies (ganglionopathies). Muscle Nerve. 2004;30(3):255-68. DOI: http://dx.doi.org/10.1002/mus.201005

Saperstein DS, Katz JS, Amato AA, Barohn RJ. Clinical spectrum of chronic acquired demyelinating polyneuropathies. Muscle Nerve. 2001;24(3):311-24. DOI: https://doi.org/10.1002/1097-4598(200103)24:3<311::AID-MUS1001>3.0.CO;2-A

Hadjivassiliou M, Rao DG, Wharton SB, Sanders DS, Grünewald RA, Davies-Jones AG. Sensory ganglionopathy due to gluten sensitivity. Neurology. 2010;75(11):1003-8. DOI: http://dx.doi.org/10.1212/WNL.0b013e3181f25ee07

Dominguez-Gonzalez C, Martinez-Salio A, Gordo-Manas R, Ballesteros-Plaza L, Hernandez-Lain A, Hernandez-Gallego J. Sensory ganglionopathy as a manifestation of celiac disease. Rev Neurol. 2007;45(2):91-4.8.

Muppidi S, Vernino S. Paraneoplastic neuropathies. Continuum (Minneap Minn). 2014;20(5 Peripheral Nervous System Disorders):1359-72. DOI: http://dx.doi.org/10.1212/01.CON.0000455876.53309.ec9

Mygland A. Approach to the patient with chronic polyneuropathy. Acta Neurol Scand. 2007:115(Suppl. 187):15-21. DOI: http://dx.doi.org/10.1111/j.1600-0404.2007.00841.x

Published

2015-12-01

Issue

Section

Case Report

How to Cite

1.
Gomes CRA, Silva BN, Ferrão GC, Nunes ASF, Ramos A de M, Chung TM, et al. Ganglionopathy as the initial manifestation of neoplastic lung disease: a case report. Acta Fisiátr. [Internet]. 2015 Dec. 1 [cited 2024 May 15];22(4):212-4. Available from: https://www.revistas.usp.br/actafisiatrica/article/view/122518